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Author Topic: Vaginal Progesterone Reduces Preterm Birth  (Read 1852 times)


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Vaginal Progesterone Reduces Preterm Birth
« on: March 09, 2018 at 05:13 AM »
Hi ladies!

Great news! Just in from the press (American Journal of Obstetrics and Gynecology):
" Vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with
a short cervix: a meta-analysis of individual patient data"
Authors: Roberto Romero, MD, DMedSci; Agustin Conde-Agudelo, MD, MPH, PhD; Eduardo Da Fonseca, MD; John M. O’Brien, MD; Elcin Cetingoz, MD; George W. Creasy, MD; Sonia S. Hassan, MD; Kypros H. Nicolaides, MD

This is a great article: evidence-based, which means hard facts, no "expert opinions". Plus, the authors are super-stars of obstetrics, multi-published, OB royalty =)

I can't upload the file because of size restrictions, but PM me and I'll send it to anyone interested.

Basically, their findings are:
- vaginal progesterone reduces the odds of preterm birth if you have a short cervix (under 25mm after 14 weeks)
- it also reduces poor neonatal outcomes (NICU admission, neonatal health problems, etc..)
- no increase in maternal complications
- no increase in neurodevelopmental problems at 2 years of age.

So look out for options! This is a great support if you want to discuss progesterone administration with your doctors.


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Re: Vaginal Progesterone Reduces Preterm Birth
« Reply #1 on: August 06, 2018 at 04:54 PM »
This is great news! Thank you